American Neuropsychiatric Association (ANPA)
TitleLevodopa activation fMRI study of Tourette syndrome
InvestigatorKevin J. Black, M.D.
Other InvestigatorsT. Hershey
Brief AbstractTwo study days (after screening) involving cognitive activation fMRI after a single dose of either i.v. levodopa on one day and saline on the other, after oral carbidopa. (See for our pilot study results.)
Inclusion/Exclusion CriteriaAdults (age 18-55); DSM-IV-TR Tourette's disorder or chronic tic disorder; no significant exposure to neuroleptics ever
Opportunities for CollaborationPossibly, if someone has lots of neuroleptic-naive adult tic patients who would be willing to come to St. Louis.

American Neuropsychiatric Association
• Menninger Clinic • 12301 Main St. • Houston, TX 77035 • 713.275.5777