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| Title | Brain Imaging and Treatment of Persistent Lyme Encephalopathy |
| Investigator | Brian A. Fallon, MD |
| Other Investigators | Harold Sackeim, Ronald Van Heertum, Robert de la Paz |
| Contact Email | BAFallon@aol.com |
| Brief Abstract | Three main goals: First, what can we learn about the effect of Borrelia burgdorferi on the brain via the techniques of MRI and PET (FDG & O-15)? Second, does a repeated longer course of IV antibiotic therapy help to improve cognitive deficits? Third, are there markers at baseline that are associated with clinical response? |
| Inclusion/Exclusion Criteria | Inclusion:
1. Age 18-60
2. CDC Lyme Disease
3. Current Western blot positivity
4. Past treatment with at least 4 weeks of IV antibiotics
5. Current Memory Problems
Exclusion:
1. Hx of other major medical problems
2. Pre-Lyme cognitive disorder
3. Allergy to penicillins
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| Opportunities for Collaboration | I welcome collaboration to help clarify the complexities of this illness. |
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American Neuropsychiatric Association • 700 Ackerman Road, Suite 625 • Columbus, OH 43202 • 614.447.2077
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